The Opioid Response Project

Medication Initiatives

Medication Initiatives:

These resources provide information about medication-assisted treatment (MAT), medication disposal, and naloxone (overdose reversal) in NC and beyond. Communities may use these resources to access MAT, disposal, or naloxone, and learn more about medication initiatives they may want to  implement in their communities.


Medication-Assisted Treatment Resources: These resources provide information on medication-assisted treatment (MAT), including its use to treat opioid use disorder (OUD), providers of MAT, and its use in jail settings.

Jail-Based Medication-Assisted Treatment: Promising Practices, Guidelines, & Resources for the Field (2018) PDF - This guidebook contains information for criminal justice professionals about the benefits and practice of MAT during incarceration. 

Medication-Assisted Treatment  (SAMHSA) - This webpage provides a thorough description of MAT, its use in treating opioid use disorder, and the different medications available for treatment. It also provides training materials and resources, as well as legal regulations and guidelines for implementing MAT.

2019 NC Drug User Health Resource Guide by Region: “Medication Assisted Treatment & Behavioral Health” & “Buprenorphine/Suboxone Providers” by region - This guide provides a list of providers by region who offer MAT, including prescribers and treatment specialists who incorporate MAT into a behavioral health treatment plan.

Project OBOT (Office Based Opioid Treatment): NC Medical Society Foundation - This resource has information about increasing MAT in office settings of primary care physicians and increasing access to opioid use disorder care.

SAMHSA Buprenorphine Practitioner Locator - A national, interactive locator for practitioners prescribing buprenorphine, one of the accepted medications used for MAT.

UNC ECHO Project - This project focuses on understanding barriers to MAT, implementing it in more communities via community and practitioner education, and expanding access to MAT to all 100 NC counties. They provide web-based clinics for participants and providers as well as other resources for those interested in learning more about MAT.

Using Medication-Assisted Treatment in Jails: A North Carolina Focus (2019) PDF - A NC-focused quick facts guide to MAT in jails to improve the public health and other outcomes of inmates experiencing opioid use disorder. It includes a case study of the Durham County Detention Center, which implemented MAT.


Medication Disposal Resources: These resources provide information on where to safely dispose of prescription medications, including opioids, to prevent misuse.

DisposeRx - Available at Walmart pharmacies, DisposeRx contains ingredients that, according to the manufacturer, when emptied into a pill bottle with warm water, dissolve medication and enable patients to responsibly dispose of leftover medications in their trash.

NC Disposal Initiative - This initiative provides drop boxes for safe medication disposal, including an interactive map of NC drop box locations.

 Operation Medicine Drop - This organization helps prevent accidental poisonings and drug misuse, while protecting local water systems from medication pollution, by providing safe and secure ways for people to dispose of unwanted prescription and over-the-counter medications.


Naloxone-Related Resources: The below resources contain information about naloxone, a medication that can reverse opioid overdoses. These include what naloxone is and how it works; how it can be provided and accessed; and training on how to use naloxone to treat an individual experiencing an overdose.

Direct Relief - Direct Relief works with Pfizer to make up to 1 million doses of overdose-reversing Naloxone available at no cost to community health centers, free and charitable clinics, public health departments, and other nonprofit providers nationwide.

Naloxofind: App to Find Naloxone (informational PowerPoint about the app) - NaloxoFind is a free app for Apple and Android smartphones that enables anyone around an overdose victim to send anonymous requests to nearby naloxone carriers or locate public naloxone locations.

Naloxone Saves - An overview of how NC responds to the opioid epidemic, where data about the epidemic can be found, as well as where naloxone can be procured both by pharmacists and community distributors.

North Carolina Harm Reduction Coalition- How to Use Naloxone Guide - Poster-style how-to guide on how to respond to an opioid overdose, including administering naloxone and reporting its use.

North Carolina Naloxone Distribution Toolkit (2019) PDF - This resource was created by the North Carolina Division of Public Health Injury and Violence Prevention Branch to guide local health departments, coalitions, and community organizations through the process of implementing a distribution standing order for naloxone.

Prescribe to Prevent - Resource for medication prescribers to learn how to begin prescribing naloxone rescue kits, as well as resources about the medicine itself.

Project Lazarus Naloxone Training Video - This video demonstrates how to administer naloxone through various nasal, auto-injector, and intra-muscular devices.